Origin: from ♀ C57BL/6JRj and ♂ CBA/JRj (from JANVIER LABS) 

Strain name: B6CBAF1/JRj 

Type : Hybrid mouse 

Colour and related genotype: Agouti mouse, A/a, Pde6brd1/+ MHC: Haplotype H2b/k 

Breeding: Easy to rear, good maternal instinct

These F1 hybrids are the result of a cross between a C57BL/6JRj female and a CBA/JRj male. F1 hybrids are heterozygous at every locus (provided that the parental strains have different alleles). As is the case with inbred strains, they are genetically and phenotypically uniform. F1 hybrids are often used for their hybrid vigour (resistance and acitivity). They are especially interesting as genetic background (vigour and repeatability of genetic inheritance) for harmful phenotype models, for tissue transplantation, to determine mechanisms of inheritance, to create or improve expression of polygenic disease. F1 hybrid females are used at JANVIER LABS’s as surrogate mothers for embryo transfer thanks to their maternal qualities.