생명공학 분야 최고의 파트너, 라온바이오(주)
제품 상세정보
Origin: Zentralinstitut für Versuchstierzucht (Hannover) - 1988 (F200)
Strain name: CBA/JRj
Type : Inbred mouse
Colour and related genotype: Agouti mouse
Breeding: Difficult to rear
This CBA and its major substrains are known for their use in numerous research fields such as
audition, immunology, gerontology, oncology or pharmacology. It has a few bristles on foot pads and
some molars can be frequently be found absent.
The CBA is therefore broadly distributed, especially due its high spontaneous disease occurrence and
its life-span going from 69 up to 117 weeks depending
on the substrain and sex. By crossing a DBA male with a Bagg albino female, Strong created the CBA
in 1920. The descendants of this cross were both CBA and C3H. Starting from there, C3H were
selected for their high mammary tumor incidence while the CBA were selected for their low tendency
to develop a low incidence instead.
If the CBA has relatively good breeding performance (except for the N substrain) along with good
litter sizes, it is not necessarily easy to breed.
Except for the mammary tissue, it has a high gross tumor rate and incidence, and when fed lipids at a
high level, CBA tend to have a low propensity to atheroma.